Found this on the web, thought it was basic but to the point:
Note: Jet sizes increase in different increments. A 125
main jet may have a 127, 127.5, or 130 as the NEXT
larger jet size.
Keihin, Mikuni and Aftermarket jet kits use different
numbers to indicate jet orifice size. A 125 Keihin jet is
not the same orifice size as a 125 Mikuni jet. Jets also
have different thread sizes. Always use the same jet
design and brand as original.
Starting point for stock engines with bolt-on
modifications: Increase main jet size by at least 3
sizes. Move needle clip down one position (richer).
Starting point for modified engines with larger
displacement: Increase main jet size by at least 4.
Move needle clip down one position (richer). Pilot
jet usually stays stock.
JETTING BASICS
It is the responsibility of the owner to determine
proper jetting for their engine.
These jetting specifications are designed as a rule of thumb. They are
in no way absolute. Variations in air density, specific gravity of fuel, altitude
and other engine modifications play a large part in jetting. Newly
built engines need rich jetting during break-in. Do not jet for power
until an engine is broken-in.
Plug reading may not work. Revving the engine while it is sitting in the
garage doesn't work. Other than Dyno testing, the steps below is the
simplest way you can jet your engine.
1. Find a gentle slope that you can ride in 2nd or 3rd gear. Look for
something that will put a reasonable load on the engine. This will be
your “dyno”.
2. A basic outline of which jet is active at a particular throttle setting:
Pilot Jet = 0 to 1/4 throttle. Needle = 1/4 to 3/4 throttle. Main Jet = 3/4
to Full Throttle.
● Changing the Main Jet size won't affect how your engine idles or
runs at 1/4 throttle.
● Engine RPM isn't what determines which jet is active - throttle position
does.
3. Make the recommended jetting changes. Always start rich and
work leaner.
4. Start and warm up the engine, then ride your "dyno hill". Any point
where you feel the engine stumble or hesitate indicates a tuning problem.
Note the throttle position and modify the corresponding jet (1/4 to
1/2 throttle = needle. 3/4 throttle or more = main jet).
5. Only change jetting by 1 step at a time, and 1 circuit at a time (don't
change needle and main at the same time). Re-check after every
change.
6. Once the engine runs smoothly throughout, you're jetted!
If you ever notice an abrupt loss of power, or
engine sounds change, shut it down.